Human Adipose-derived mesenchymal stem cells promote lymphocyte apoptosis and alleviate atherosclerosis via miR-125b-1-3p/BCL11B signal axis | Zendy

Chaowen Yu | Zendy; Wenbo Tang | Zendy; Ran Lu | Zendy; Tao Yuan | Zendy; Tiancai Ren | Zendy; Yong Gao | Zendy

Open Access

Human Adipose-derived mesenchymal stem cells promote lymphocyte apoptosis and alleviate atherosclerosis via miR-125b-1-3p/BCL11B signal axis

Author(s) -

Chaowen Yu,

Wenbo Tang,

Ran Lu,

Tao Yuan,

Tiancai Ren,

Yong Gao

Publication year - 2021

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-21-49

Subject(s) - medicine , mesenchymal stem cell , adipose tissue , apoptosis , lymphocyte , cancer research , stem cell , microbiology and biotechnology , immunology , pathology , genetics , biology

Mesenchymal stem cells (MSCs) have shown great potential in the treatment of cardiovascular diseases, with fat being a more accessible source of MSCs. This study investigated the effect of human adipose-derived mesenchymal stem cells (hMSCs-Ad) exosomes on T lymphocytes and its role in atherosclerosis (AS).

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