Open AccessLower serum irisin levels are associated with the increasing mortality of cardiovascular and cerebrovascular diseases in hemodialysis patients
Author(s) -
Xingtong Dong,
Wenjing Fu,
Yinghui Deng,
Linpei Jia,
Na Lin,
Wen Li,
Aihua Zhang
Publication year - 2021
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 19
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-21-406
Subject(s) - medicine , myokine , adipokine , hemodialysis , kidney disease , disease , population , endocrinology , leptin , obesity , skeletal muscle , environmental health
Irisin is a recently discovered myokine/adipokine and lower levels of irisin were proved to be associated with adverse outcomes of cardiovascular and cerebrovascular diseases (CCVD) in general population. A significant decrease of irisin concentrations were also detected in patients with chronic kidney disease (CKD). In the present study, we investigated whether the serum irisin levels were associated with cardiovascular and cerebrovascular mortality in hemodialysis (HD) patients.
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