The efficacy of therapeutic apheresis in patients with refractory neuromyelitis optica spectrum disorders: a single-center retrospective study | Zendy

Leiying Zhang | Zendy; Yuan Zhuang | Zendy; Xiaomin Liu | Zendy; Quangang Xu | Zendy; Lingling Zhou | Zendy; Liyang Zou | Zendy; Ying Jiang | Zendy; Jing Tian | Zendy; Huan Yao | Zendy; Hongxu Chi | Zendy; Xuede Qiu | Zendy; Tianxin Yang | Zendy; Deqing Wang | Zendy; Yang Yu | Zendy

Open Access

The efficacy of therapeutic apheresis in patients with refractory neuromyelitis optica spectrum disorders: a single-center retrospective study

Author(s) -

Leiying Zhang,

Yuan Zhuang,

Xiaomin Liu,

Quangang Xu,

Lingling Zhou,

Liyang Zou,

Ying Jiang,

Jing Tian,

Huan Yao,

Hongxu Chi,

Xuede Qiu,

Tianxin Yang,

Deqing Wang,

Yang Yu

Publication year - 2021

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-21-177

Subject(s) - medicine , refractory (planetary science) , neuromyelitis optica , apheresis , optic neuritis , transverse myelitis , therapeutic plasma exchange , myelitis , multiple sclerosis , single center , pediatrics , dermatology , surgery , immunology , psychiatry , spinal cord , platelet , physics , astrobiology

Neuromyelitis optica spectrum disorders (NMOSD) are associated with recurrent episodes of optic neuritis and transverse myelitis, often resulting in high attack-related disability. Therapeutic apheresis has been recommended as a second-line treatment for steroid-refractory NMOSD. To assess the efficacy and safety of two apheresis techniques, lymphoplasmapheresis (LPE) and therapeutic plasma exchange (TPE), in refractory NMOSD and to provide a new treatment option for patients with refractory NMOSD.

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