Open AccessMolecular mechanism of Wutou Decoction in the treatment of osteoarthritis: a bioinformatics and molecular docking study
Author(s) -
BoZhao Yan,
Di Luo,
Jiacheng Li,
XueZhen Liang,
Bo Xu,
Gang Li
Publication year - 2021
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 19
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-21-1691
Subject(s) - medicine , osteoarthritis , docking (animal) , bioinformatics , mechanism (biology) , pharmacology , alternative medicine , pathology , philosophy , epistemology , nursing , biology
Osteoarthritis (OA) is a chronic joint disease characterized by cartilage destruction and periarticular osteophyte formation. One therapeutic option for this condition, the Wutou Decoction (WTD) Chinese medicine formula, is satisfactory in its efficacy. Here, we used bioinformatic and molecular docking techniques to investigate the mechanism of action of WTD in the treatment of OA.
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