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Lower levels of interleukin-35 in patients with prophase of liver failure are associated with progression to liver failure
Author(s) -
Li Chen,
Wei Sun,
Yan Wang,
Xiaoping Huang,
Jianhe Gan
Publication year - 2021
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-21-1680
Subject(s) - medicine , flow cytometry , liver failure , gastroenterology , cytokine , clinical significance , interleukin 6 , immune system , interleukin , immunology
Cytokines play critical roles in the inflammatory processes underlying liver failure. The relevance of interleukin-35 (IL-35), an anti-inflammatory cytokine, in liver failure remains uncharacterized. This study was conducted to investigate whether the IL-35 level in patients with prophase of liver failure (PLF) is associated with prognosis and the possible mechanism of immune regulation for IL-35.

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