Chinese medicine Bazi Bushen capsule improves lipid metabolism in ovariectomized female ApoE−/− mice | Zendy

Dan Huang | Zendy; Huawei Hu | Zendy; Liping Chang | Zendy; Shen Liu | Zendy; Junqing Liang | Zendy; Yanfei Song | Zendy; Xindong Wang | Zendy; Hui Zhang | Zendy; Cong Wei | Zendy; Yiling Wu | Zendy

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Chinese medicine Bazi Bushen capsule improves lipid metabolism in ovariectomized female ApoE−/− mice

Author(s) -

Dan Huang,

Huawei Hu,

Liping Chang,

Shen Liu,

Junqing Liang,

Yanfei Song,

Xindong Wang,

Hui Zhang,

Cong Wei,

Yiling Wu

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-20-906

Subject(s) - medicine , ovariectomized rat , endocrinology , estrogen , phytoestrogens , menopause , lipid metabolism , apolipoprotein e , dyslipidemia , blood lipids , estrogen receptor , diabetes mellitus , cholesterol , breast cancer , disease , cancer

Dyslipidemia is one of the mechanisms of atherosclerosis (AS). Depletion of estrogen plays a key role in the pathogenesis of postmenopausal AS in women, and the blood lipid levels of women are closely related to endogenous estrogen levels. Phytoestrogens (PEs) exert estrogenic effects, including protection against AS, without the adverse effects of estrogen administration. Bazi Bushen capsule (BZBS) is a traditional Chinese medicine herbal compound prescription that has been shown to contain 11 unique PEs. In the present study, we assessed the effects of BZBS against lipid metabolism disorders.

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