6-gingerol alleviates inflammatory injury in DSS-induced ulcerative colitis mice by regulating NF-κB signaling | Zendy

Yingyue Sheng | Zendy; Tielong Wu | Zendy; Yuanyuan Dai | Zendy; Linlin Xu | Zendy; Zhong Yao | Zendy; Yuzheng Xue | Zendy; Yaozhou Tian | Zendy

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6-gingerol alleviates inflammatory injury in DSS-induced ulcerative colitis mice by regulating NF-κB signaling

Author(s) -

Yingyue Sheng,

Tielong Wu,

Yuanyuan Dai,

Linlin Xu,

Zhong Yao,

Yuzheng Xue,

Yaozhou Tian

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-20-903

Subject(s) - immunohistochemistry , ulcerative colitis , medicine , colitis , blot , inflammatory bowel disease , mesalazine , pharmacology , pathology , immunology , chemistry , biochemistry , disease , gene

The imbalance of Treg/Thl7 cells and inflammatory injury are believed to be involved in the development of ulcerative colitis (UC). Meanwhile, 6-gingerol has been reported to alleviate intestinal inflammatory damage in mice models, but the underlying mechanism remains elusive.

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