Role of MK2 signaling pathway mediating microglia/macrophages polarization in chronic compression injury of cervical spinal cord | Zendy

Lei Yu | Zendy; Hongxing Song | Zendy; Xiutong Fang | Zendy; Yali Hu | Zendy

Open Access

Role of MK2 signaling pathway mediating microglia/macrophages polarization in chronic compression injury of cervical spinal cord

Author(s) -

Lei Yu,

Hongxing Song,

Xiutong Fang,

Yali Hu

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-20-396

Subject(s) - medicine , microglia , spinal cord injury , signal transduction , spinal cord , neuroscience , immunology , inflammation , microbiology and biotechnology , psychiatry , biology

The role of inflammatory factors in the chronic compression injury of cervical spinal cord has drawn more attenion recently, however, the mechanism of which is still unclear. In this study, microglia/ macrophages polarization in the inflammatory responses to the injury and its regulation by MK2 signaling pathway have been investigated.

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