Naoluo Xintong capsule ameliorates apoptosis induced by endoplasmic reticulum stress in rats with cerebral ischemia/ reperfusion injury | Zendy

Sipeng Wu | Zendy; Xinxin Piao | Zendy; Ning Wang | Zendy; Yan Zhai | Zendy

Open Access

Naoluo Xintong capsule ameliorates apoptosis induced by endoplasmic reticulum stress in rats with cerebral ischemia/ reperfusion injury

Author(s) -

Sipeng Wu,

Xinxin Piao,

Ning Wang,

Yan Zhai

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-20-387

Subject(s) - creb , medicine , tunel assay , apoptosis , unfolded protein response , reperfusion injury , ischemia , pharmacology , endoplasmic reticulum , chop , western blot , terminal deoxynucleotidyl transferase , microbiology and biotechnology , biochemistry , biology , immunohistochemistry , lymphoma , gene , transcription factor

Naoluo Xintong (NLXT) capsuleis a newly developed drug recorded in the Chinese Pharmacopoeia. It is derived from traditional Chinese medicine (TCM) NLXT decoction, and has been widely used to treat cerebrovascular diseases in clinic. However, it is currently unknown whether it improve cerebral ischemia reperfusion (I/R) injury.

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