Utilizing network pharmacology to explore the underlying mechanism of Qiangzhi decoction in treating Tourette’s syndrome
Author(s) -
ChengDi Dong,
Hongshuo Shi,
Qian Chu,
Yukun Li,
Huishan Shi,
Anran Song,
Zhaojun Yan
Publication year - 2020
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 19
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-20-2158
Subject(s) - kegg , tourette syndrome , medicine , systems pharmacology , decoction , traditional chinese medicine , mechanism (biology) , computational biology , pharmacology , dopamine , traditional medicine , gene , biology , psychiatry , genetics , alternative medicine , gene ontology , epistemology , pathology , philosophy , gene expression , drug
Tourette's syndrome (TS) is a neurodevelopmental condition characterized by multiple motor and vocal tics. Qiangzhi decoction (QD), a well-known herbal decoction, has been used in treating TS in China for decades. We have found relevance between the indications of QD and the classic symptoms of TS. The pharmacological mechanisms of QD in treating TS are still unclear.
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