Open AccessProtective effect of lutein on oxidative stress damage caused by acute PM2.5 exposure in rats
Author(s) -
Ximin Chen,
Yuexiao Chen,
Yuan Chen,
Xin Wang,
Mei He
Publication year - 2020
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 19
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-20-1138
Subject(s) - medicine , lutein , oxidative stress , oxidative damage , toxicology , carotenoid , food science , biology , chemistry
Particulate matter (PM) is the sum of organic and inorganic substances suspended in air. Particles with a diameter equal to or smaller than 2.5 μm (PM2.5) can induce extensive oxidative stress damage in lung tissues. Lutein can prevent oxidative stress and the production of pro-inflammatory cytokines. However, its role in lung injury induced by PM2.5 is still unclear. This study used lutein to intervene in lung injury induced by PM2.5 in rats to confirm the protective function of lutein in PM2.5- induced lung injury.
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