Open AccessMMP-9 regulates CX3CL1/CX3CR1 in the early phase of neuropathic pain in chronic sciatic nerve constriction injury (CCI) rats
Author(s) -
Li Zhao,
Congzhong Song,
Yaqin Huang,
Weiping Lei,
Jianliang Sun
Publication year - 2020
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 19
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-20-1078
Subject(s) - medicine , neuropathic pain , sciatic nerve , constriction , nerve injury , anesthesia , cx3cl1 , chronic pain , sciatic nerve injury , physical therapy , receptor , chemokine , chemokine receptor
To observe the effects of MMP-9 (matrix metalloproteases-9) on the mechanical allodynia and thermal hyperalgesia and the expression of CX3CL1 (CX3C chemokine ligand 1) protein in the spinal dorsal root ganglion (DRG) in rats with chronic sciatic nerve constriction injury (CCI).
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