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Screening for and combining serum intestinal barrier-related biomarkers to predict the disease severity of AECOPD
Author(s) -
Jiuheng Yin,
Shuai Wang,
Yuan Qiu,
Enlai Jiang,
Guangsheng Du,
Wensheng Wang,
Pengyuan Xu,
Hua Yang,
Mingdong Hu,
Weidong Xiao
Publication year - 2020
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-20-1060
Subject(s) - medicine , copd , citrulline , gastroenterology , pulmonary disease , receiver operating characteristic , prospective cohort study , logistic regression , arginine , biochemistry , amino acid , chemistry
In the patients with AECOPD, the gut displays ischemia, anoxia and oxidative stress, which lead to the intestinal barrier failure. Therefore, it is desirable to screen for effective intestinal barrier-related biomarkers to monitor the disease severity.

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