Elevated plasma histone H4 level predicts increased risk of mortality in patients with sepsis | Zendy

Nianfang Lu | Zendy; Li Jiang | Zendy; Bo Zhu | Zendy; Degang Yang | Zendy; Ruiqiang Zheng | Zendy; Jun Shao | Zendy; Xiuming Xi | Zendy

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Elevated plasma histone H4 level predicts increased risk of mortality in patients with sepsis

Author(s) -

Nianfang Lu,

Li Jiang,

Bo Zhu,

Degang Yang,

Ruiqiang Zheng,

Jun Shao,

Xiuming Xi

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-20-1011

Subject(s) - sepsis , medicine , histone , biomarker , pathogenesis , intensive care medicine , immunology , gene , genetics , biology

Histones play a vital role in the pathogenesis of sepsis. However, studies on histones and the prognosis of sepsis patients are scarce. This study aims to investigate the relationship between histones and other biomarkers of sepsis. Furthermore, we aim to determine the role histones play in the prognosis of sepsis patients to explore the possibility of using them as a potential biomarker of sepsis.

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