Sophocarpine prevents cigarette smoke-induced restenosis in rat carotid arteries after angioplasty | Zendy

Genhuan Yang | Zendy; Rong Zeng | Zendy; Xitao Song | Zendy; Tianjia Li | Zendy; Changwei Liu | Zendy; Leng Ni | Zendy

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Sophocarpine prevents cigarette smoke-induced restenosis in rat carotid arteries after angioplasty

Author(s) -

Genhuan Yang,

Rong Zeng,

Xitao Song,

Tianjia Li,

Changwei Liu,

Leng Ni

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-19-568

Subject(s) - medicine , restenosis , cardiology , carotid arteries , angioplasty , cigarette smoke , coronary arteries , artery , stent , environmental health

Cigarette smoking is one of the main predisposing factors for atherosclerosis, which can lead to vascular inflammation. Emerging research has demonstrated that the rate of restenosis is increased following angioplasty in smokers. Sophocarpine, one of the Sophora alkaloids, can play the antiinflammatory role in cells. This study aimed to assess whether sophocarpine can alleviate the restenosis induced by cigarette smoke in rats post-angioplasty.

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