Protective effects of resveratrol liposomes on mitochondria in substantia nigra cells of parkinsonized rats | Zendy

Jianming Chen | Zendy; Qingquan Liu | Zendy; Yanchun Wang | Zendy; Yuhong Guo | Zendy; Xiaolong Xu | Zendy; Po Huang | Zendy; Bo Lian | Zendy; Rui Zhang | Zendy; Yishan Chen | Zendy; Yanxiang Ha | Zendy

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Protective effects of resveratrol liposomes on mitochondria in substantia nigra cells of parkinsonized rats

Author(s) -

Jianming Chen,

Qingquan Liu,

Yanchun Wang,

Yuhong Guo,

Xiaolong Xu,

Po Huang,

Bo Lian,

Rui Zhang,

Yishan Chen,

Yanxiang Ha

Publication year - 2021

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-19-426

Subject(s) - substantia nigra , resveratrol , mitochondrion , neuroprotection , pars compacta , cytochrome c , pink1 , apoptosis , apoptosis inducing factor , pharmacology , microbiology and biotechnology , parkinson's disease , inner mitochondrial membrane , medicine , parkin , dopaminergic , chemistry , biology , biochemistry , programmed cell death , dopamine , disease , caspase

Parkinson's disease (PD) is a central nervous system degenerative disease. The progressive death of dopaminergic neurons is closely correlated to mitochondrial dysfunction. Resveratrol contains three hydroxyl groups, and has a strong neuroprotective effect. This study aimed to investigate the protective effect of resveratrol liposome on mitochondria of substantia nigra cells in Parkinsonized rats through experiment.

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