DNA methylation changes in the hippocampus of learning and memory disorder offspring rats of lead exposure during pregnant and lactation period
Author(s) -
Tao Hong,
Shou-Ming Li,
Bo Jia,
Yun Huang,
Shu Kun,
Ke-Wang Yuan,
Lai Chen,
Long-Xue Li,
Li Liu,
Zhiyong Liu
Publication year - 2020
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 19
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-19-421
Subject(s) - offspring , epigenetics , medicine , lactation , hippocampus , memory impairment , dna methylation , pregnancy , period (music) , neuroscience , physiology , psychiatry , cognition , genetics , biology , gene expression , gene , physics , acoustics
Pregnant female rats exposed to lead may give birth to offspring with learning and memory disorders. Many studies have shown that there are many mechanisms that cause learning and memory impairment. Epigenetic mechanisms may play an important function in the learning and memory impairment.
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