Thalidomide inhibits the gene promoter of connective tissue growth factor in human embryonic lung fibroblasts | Zendy

Yonghui Wu | Zendy; Libao Liu | Zendy; Jian Zhang | Zendy; Lei Huang | Zendy; Shaohong Huang | Zendy; Jinyuan He | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Thalidomide inhibits the gene promoter of connective tissue growth factor in human embryonic lung fibroblasts

Author(s) -

Yonghui Wu,

Libao Liu,

Jian Zhang,

Lei Huang,

Shaohong Huang,

Jinyuan He

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-19-398

Subject(s) - ctgf , luciferase , transforming growth factor , thalidomide , medicine , growth factor , transfection , connective tissue , fibroblast , cancer research , fibrosis , promoter , gene , microbiology and biotechnology , gene expression , biology , immunology , pathology , cell culture , receptor , biochemistry , genetics , multiple myeloma

The etiology and pathogenesis of idiopathic pulmonary fibrosis (IPF) remain unclear, and the early detection and treatment are vital to the prognosis of IPF patients. It's necessary to investigate the effect of thalidomide on the gene promoter activation of connective tissue growth factor (CTGF) induced by transforming growth factor-β1 (TGF-β1) in human embryonic lung fibroblast (HELF).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research