Fabrication of Microneedle Mimicking Mosquito Proboscis Using Nanoscale 3D Laser Lithography System
Author(s) -
Masato Suzuki,
Takahiro Sawa,
Tomokazu Takahashi,
Seiji Aoyagi
Publication year - 2015
Publication title -
international journal of automation technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.513
H-Index - 18
eISSN - 1883-8022
pISSN - 1881-7629
DOI - 10.20965/ijat.2015.p0655
Subject(s) - proboscis , materials science , lithography , soft lithography , optics , fabrication , maskless lithography , laser , maxilla , nanoscopic scale , biomedical engineering , anatomy , nanotechnology , resist , optoelectronics , electron beam lithography , biology , engineering , medicine , physics , alternative medicine , pathology , layer (electronics)
A mosquito’s proboscis, which is used for sucking blood, consists of seven complicated parts. For example, the labrum has a hollow structure, and the maxillae have micrometer-sized tooth like projections on its tip. In this study, microneedles imitating one labium and two maxillae were fabricated using a precision three-dimensional laser lithography system “Nanoscribe.” The maximum length of the fabricated microneedle was 2.0 mm, the minimum length required to reach human capillary blood vessel underneath the epidermis.
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