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Inflammatory Cytokines and Non-Alcoholic Fatty Liver Disease (NAFLD) in Obese Children and Adolescents
Author(s) -
Silvana Silvana,
Ney BoaSorte,
Crésio Alves,
Patrícia Mendes,
Carlos Brites,
Luciana da Silva
Publication year - 2018
Publication title -
nutrición hospitalaria
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 53
eISSN - 1699-5198
pISSN - 0212-1611
DOI - 10.20960/nh.1317
Subject(s) - medicine , fatty liver , insulin resistance , body mass index , proinflammatory cytokine , obesity , overweight , waist , steatosis , endocrinology , gastroenterology , disease , inflammation
Non-alcoholic fatty liver disease is characterized by the intrahepatic deposition of fat. It is the most prevalent liver disease in the world, affecting obese children and adolescents. Its pathophysiology is not fully understood, although it is often related to insulin resistance. This in turn would be due to an inflammatory condition common to obesity. Thus, the objective of this study was to describe the behavior of proinflammatory cytokines in obese children and adolescents, with and without non-alcoholic fatty liver disease.

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