Appetite hormones in children and adolescents with cancer: a systematic review of observational studies | Zendy

Ana Paula Trussardi Fayh | Zendy; Ágnes Denise de Lima Bezerra | Zendy; Rogério Friedman | Zendy

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Appetite hormones in children and adolescents with cancer: a systematic review of observational studies

Author(s) -

Ana Paula Trussardi Fayh,

Ágnes Denise de Lima Bezerra,

Rogério Friedman

Publication year - 2018

Publication title -

nutrición hospitalaria

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.31

H-Index - 53

eISSN - 1699-5198

pISSN - 0212-1611

DOI - 10.20960/nh.1221

Subject(s) - leptin , ghrelin , medicine , cancer , appetite , hormone , malnutrition , observational study , obesity , pediatric cancer , cachexia , oncology

Malnutrition in children with cancer is a significant risk factor for negative outcomes, but in the clinical practice setting, it is difficult to pinpoint which factors operate to cause substantial weight loss and malnutrition in a given patient. Appetite-related hormones like ghrelin and leptin are among possible mediators. However, only few studies have examined the role of these hormones in pediatric patients with cancer to date. Thus, the purpose of this study was to systematically review possible changes in the levels of appetite hormones, specially leptin and ghrelin, in pediatric patients with cancer.

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