Open AccessNutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot
Author(s) -
Rosa María Martínez García,
Rosa María Chacón,
Ana María Lorenzo Mora,
Rosa María Ortega Anta
Publication year - 2021
Publication title -
nutrición hospitalaria
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 53
eISSN - 1699-5198
pISSN - 0212-1611
DOI - 10.20960/nh.03800
Subject(s) - medicine , wound healing , glutamine , glycemic , micronutrient , arginine , malnutrition , diabetes mellitus , vitamin c , vitamin , medical nutrition therapy , diabetic foot , surgery , pharmacology , endocrinology , amino acid , biochemistry , chemistry , pathology
Nutrition plays an essential role in chronic wound healing as extra nutrients are needed for tissue repair and to restore losses through wound exudate. Insufficient intake of energy, protein, antioxidants (vitamin C, A, and zinc) and vitamin D are common in patients with chronic wounds and have been linked to delayed wound healing and dehiscence. Other risk factors such as obesity, diabetes, advanced age, corticosteroid use, and dehydration can also reduce or impede the healing process, and nutritional screening is important to identify patients with malnutrition. Proteins, amino acids (arginine, glutamine and methionine), vitamins C and A, and zinc have been used as pharmacological nutrients in pressure ulcer healing; however, omega-3 fatty acids, although they appear to slow progression, do not show improved healing rates. In patients with diabetic foot, supplementation with vitamins D, C, A, and E, magnesium, zinc, omega-3 fatty acids, and probiotics reduces ulcer size and improves glycemic control, although they have not been associated with complete healing; however, supplementation with arginine, glutamine, and β-hydroxy-β-methylbutyrate does show wound healing, although further evidence is needed to confirm these results.