Characteristics of Regulatory T cells | Zendy

Magdalena Frydrychowicz | Zendy; Maciej Boruczkowski | Zendy; Agata Kolecka-Bednarczyk | Zendy; Renata Jenek | Zendy; Joanna Rosołowska | Zendy; Agnieszka Pluto-Prądzyńska | Zendy; Grzegorz Dworacki | Zendy

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Characteristics of Regulatory T cells

Author(s) -

Magdalena Frydrychowicz,

Maciej Boruczkowski,

Agata Kolecka-Bednarczyk,

Renata Jenek,

Joanna Rosołowska,

Agnieszka Pluto-Prądzyńska,

Grzegorz Dworacki

Publication year - 2016

Publication title -

journal of medical science

Language(s) - English

Resource type - Journals

eISSN - 2353-9801

pISSN - 2353-9798

DOI - 10.20883/175

Subject(s) - il 2 receptor , chemokine , microbiology and biotechnology , receptor , immune system , effector , immunology , regulatory t cell , chemokine receptor , biology , chemistry , t cell , biochemistry

Regulatory T cells (Tregs) is heterogenic subpopulation of T cells that is able to suppress function of effector cells during the immune response. Among them are natural (nTreg) and induced Treg (Tr1, Th3, CD4 + CD25 - ). CD25, CD45Ro, CD152, GITR, LAG-3, several adhesion molecules, chemokine receptors as well as Toll-like receptors are present on the surface of Treg. Mechanism of suppression used by nTreg is not completely understood.

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