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Hepatocarcinoma with metastasis to the anterior mediastinum
Author(s) -
Rogério Camargo Pinheiro Alves,
Lorena Sagrilo Auer,
Lisa Rodrigues da Cunha Saud,
Raquel Coris Arrelaro,
Aline Carboni Casado,
Bruno Gustavo Ferreira,
Denis Szjenfeld,
Paula Poletti
Publication year - 2016
Publication title -
hepatoma research
Language(s) - English
Resource type - Journals
eISSN - 2454-2520
pISSN - 2394-5079
DOI - 10.20517/2394-5079.2016.01
Subject(s) - medicine , metastasis , pathogenesis , mediastinum , anterior mediastinum , general surgery , pathology , radiology , oncology , cancer
Liver malignancies are the sixth leading cause of cancer worldwide, whereas hepatocellular carcinoma (HCC) is the most frequent histological type of liver cancer. Extrahepatic metastasis, which rarely involves the mediastinum, is associated with poor prognosis. An 80-year-old male presenting with mild diffuse abdominal pain for 4 months, associated with hyporexia, increased abdominal volume, dry cough, and loss of 4 kg in 1 month, sought medical assistance due to hemoptysis and chest pain. Tomographic study revealed HCC with mediastinal metastasis, after which sorafenib therapy was started. Disease progressed to death 4 months after the start of the treatment.

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