Konya Bölgesinde Gastroskopi Yapılan Hastalarda Histopatolojik Bulgular ve Helicobacter Pylori Sıklığı

The aim of this study is to investigate the prevelance of Helicobacter Pylori ( H. pylori ), the relationship between helicobacter pylori prevelance and age-gender-histo-pathological findings. Material and Methods: Data of the patients, whom gastroscopy was performed between January 2012 – June 2013 secondary to any occasion and biopsy specimens were obtained from antrum-corpus, were investigated retrospectively. H. Pylori prevelance was determined at general patient group and subgroups which were allocated according to gender and age intervals. Results: Mean age of the patients was 49.3 ± 16.5. While 1057 (57.7%) of the patients were female with a mean age of 48.3 ± 16.1, 777 of the patients were male (42.2%) with a mean age of 50.1 ± 17.0. Although H. Pylori was negative at 1099 (60.1%) of the patients, it was positive at 730 (39.9%) of the patients, 314 male (40.41%) and 416 female (39.13%). H. Pylori prevelance was similar at both genders . Positivity of H. Pylori was mild at 57%, moderate at 30% and severe at 13% of the patients. At age allocated subgroups; H. Pylori positivity was 49.8%, 45.7%, 38.5%, 29.7% respectively at patients between 14–30, 31–45, 46–60 and 61–95 ages. Prevelance of H. Pylori was significantly higher at patients below the age of 45 (p=0.001). H. Pylori positivity was 47.8%, 40.7%, 27.0%, 18.5% and 6.1% respectively at patients with histo-pathological diagnosis of non-atrophic gastritis, atrophic gastritis, intestinal metaplasia and normal histology. Conclusion: H. Pylori prevelance is 39.9% at patients from Konya region, prevelance is similar at both genders, prevelance of H. Pylori is statistically significant at patients below the age of 45. KEY WORDS: Upper gastrointestinal tract endoscopy, Helicobacter Pylori, prevelance,  histo-pathology. OZET: Calismanin amaci Helicobacter pylori ( H. pylori ) sikligi, sikligin yas, cinsiyet ve histolojik bulgularla iliskisinin arastirilmasidir. Gerec ve yontem: Ocak 2012- Haziran 2013 doneminde,  endoskopi unitesinde herhangi bir nedenle gastroskopi yapilan ve antrum-korpus biyopsisi alinan hastalar geriye donuk olarak incelendi. H. pylori sikligi genel, cinsiyet ve yas gruplarina ayrilarak belirlendi. Bulgular: Calismaya alinan hastanin ortalama yasi 49.3 ± 16.5 idi. Hastalarin 1057’si (%57.7) kadin olup yas ortalamasi 48.3 ± 16.1 iken 777’si (%42.2) erkek olup yas ortalamasi 50.1 ± 17.0 idi.  H. pylori 1099 (%60.1) hastada negatif iken,  314 erkek (%40.41) ve 416 kadin (%39.13) olarak toplam 730 (%39.9) hastada pozitif bulundu. Kadin ve erkeklerde H. pylori sikligi benzerdi. H. pylori pozitifligi hastalarin %57’inde hafif, %30’unda orta, %13’unde agir siddetteydi. 14–30 yas, 31–45 yas, 46–60 yas ve 61–95 yas gruplarinda H. pylori sikligi sirasiyla %49.8, %45.7, %38.5, %29.7 idi.  45 yas alti hastalarda H. pylori sikligi anlamli derecede yuksek bulundu (p=0.001). Histotopalojik incelemede, nonatrofik gastrit, atrofik gastrit, intestinal metaplazi ve normal histoloji gozlenen hastalarda H. Pylori sikligi sirasiyla %47.8, %  40.7, % 27.0, % 18.5 ve % 6.1 idi. Sonuc: Konya bolgesinde H .pylori sikligi %39,9’ olup cinsiyetler arasinda anlamli fark yokken 45 ve alti yas hastalarda H.pylori sikligi anlamli derecede yuksek bulundu (p=0.001). ANAHTAR KELIMELER: Ust gastrointestinal endoskopi, Helicobacter pylori, prevelans, histopatoloji.