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Prader-Willi syndrome (PWS) is a genetic disorder characterized by excessive appetite with progressive obesity and growth hormone (GH) deficiency. Excessive eating causes progressive obesity with increased risk of morbidities and mortality. Although GH treatment has beneficial effects on patients with PWS, adverse events have occurred during GH treatment. Exercise potentially has a positive effect on obesity management. The purpose of this research was to examine the effects of 24-week complex exercise program on changes in body composition, blood lipid profiles, and growth factor hormone levels in a patient with PWS.

journal of exercise nutrition and biochemistry/journal of exercise nutrition and biochemisrty

Changes in body composition, blood lipid profile, and growth factor hormone in a patient with Prader–willi syndrome during 24 weeks of complex exercise: a single case study