Open AccessNeolignan Derivatives from the Flower of Magnolia biondii Pamp. and their Effects on IL-2 expression in T-cells
Author(s) -
Thi Tuyet Mai Nguyen,
Thị Thu Hà Nguyễn,
HyunSu Lee,
ChangDuk Jun,
Byung Sun Min,
Jeong Ah Kim
Publication year - 2017
Publication title -
natural product sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 25
eISSN - 2288-9027
pISSN - 1226-3907
DOI - 10.20307/nps.2017.23.2.119
Subject(s) - jurkat cells , high performance liquid chromatography , chemistry , stereochemistry , column chromatography , two dimensional nuclear magnetic resonance spectroscopy , spectral analysis , chromatography , biology , botany , traditional medicine , t cell , physics , medicine , immunology , immune system , quantum mechanics , spectroscopy
− The isolation of the MeOH extract from the flower bud of Magnolia biondii Pamp. using various column chromatographies and HPLC led to eleven neoglignan derivatives (1 11). Their structures were mainly determined by 1D and 2D NMR spectral data analysis and physiological methods. The isolated compounds (1 11) were tested for anti-allergic effects using IL-2 inhibitory assay in Jurkat T cells.
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