Screening of antioxidant and antimicrobial activities on Plectranthus spp. extracts | Zendy

Patrícia Rijo | Zendy; Mariaogueira Batista | Zendy; Marisa Matos | Zendy; Helga Rocha | Zendy; Sandra Jesus | Zendy; M. Fátima Simões | Zendy

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Screening of antioxidant and antimicrobial activities on Plectranthus spp. extracts

Author(s) -

Patrícia Rijo,

Mariaogueira Batista,

Marisa Matos,

Helga Rocha,

Sandra Jesus,

M. Fátima Simões

Publication year - 2018

Publication title -

biomedical and biopharmaceutical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.129

H-Index - 1

eISSN - 2182-2379

pISSN - 2182-2360

DOI - 10.19277/bbr.9.2.45

Subject(s) - plectranthus , traditional medicine , lamiaceae , antimicrobial , dpph , maceration (sewage) , antibacterial activity , decoction , ocimum , salvia , ocimum gratissimum , sage , phytochemistry , antioxidant , gram positive bacteria , bacteria , chemistry , botany , biology , microbiology and biotechnology , medicine , biochemistry , materials science , genetics , physics , nuclear physics , composite material

The use of medicinal plants is a widespread tendency in folk medicine. The Lamiaceae family contains several genera such as sage (Salvia), basil (Ocimum) and mint (Mentha) with a rich diversity of ethnobotanical uses. This study presents the in vitro antibacterial and antioxidant activities evaluation of five species extracts of the Plectranthus genus: P. hadiensis (vr), P. madagascarensis, P. neochilus, P. verticillatus e P. barbatus. Aqueous and acetonic extracts were obtained by five different methods: infusion, decoction, ultrasounds, microwave and maceration (10% w / v of dry plant). The highest amount of dry extract was obtained by the infusion method for Plectranthus barbatus (22,0 ± 1,0 to 33,0 ± 3,0 mg/mL). The extracts obtained were tested for their antimicrobial activity against three Gram-positive bacteria and two Gram-negative bacteria using the well diffusion method. Only the acetonic extracts of P. madagascarensis, P. hadiensis (vd) and P. verticillatus showed antibacterial activity and this was exclusively against Gram-positive bacteria. The highest antimicrobial activity was exhibited by P. madagascarensis extract with inhibition zones ranging from 23 to 36 mm. The antioxidant activity of the extracts was qualitatively determined using the 2,2-diphenyl-l-picrylhydrazyl (DPPH) radical assay in tlc and yielded positive results for the majority of the extracts studied.

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