A didactic approach for quantification of diazepam tablets by UV spectrophotometry | Zendy

Patrícia Rijo | Zendy; Lara Ribeiro | Zendy; Ana S. Fernandes | Zendy; Célia Faustino | Zendy

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A didactic approach for quantification of diazepam tablets by UV spectrophotometry

Author(s) -

Patrícia Rijo,

Lara Ribeiro,

Ana S. Fernandes,

Célia Faustino

Publication year - 2014

Publication title -

biomedical and biopharmaceutical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.129

H-Index - 1

eISSN - 2182-2379

pISSN - 2182-2360

DOI - 10.19277/bbr.11.1.83

Subject(s) - spectrophotometry , diazepam , chromatography , chemistry , medicine , anesthesia

The present paper describes a simple laboratory procedure for the quantification of diazepam, a central nervous system depressant benzodiazepine, by ultraviolet spectroscopy. Standard solutions of diazepam, prepared from a stock solution, were used to construct a calibration curve. Commercial tablets of diazepam were then analysed and the results obtained were in accordance with the expected percentage range of the manufacturer’s claim and with the specifications of the Portuguese Pharmacopeia.

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