MUTAGENICITY ASSESSMENT OF AQUATIC PRIORITY CONTAMINANTS | Zendy

Letícia de Jesus Ferreira | Zendy; Gisela de Aragão Umbuzeiro | Zendy; JOSE RICARDO ROSSETTO MARTINS ZWARG | Zendy; Daniel Alexandre Morales | Zendy

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MUTAGENICITY ASSESSMENT OF AQUATIC PRIORITY CONTAMINANTS

Author(s) -

Letícia de Jesus Ferreira,

Gisela de Aragão Umbuzeiro,

JOSE RICARDO ROSSETTO MARTINS ZWARG,

Daniel Alexandre Morales

Publication year - 2017

Publication title -

anais do congresso de iniciação científica da unicamp

Language(s) - English

Resource type - Conference proceedings

ISSN - 2447-5114

DOI - 10.19146/pibic-2017-78097

Subject(s) - contamination , environmental science , environmental chemistry , computer science , chemistry , biology , ecology

The purpose of this work was to evaluate the mutagenic activity of ten priority compounds that were identified in the Danube River Basin in Europe for the construction of a database. The protocol used is a new miniaturization version of the Salmonella/microsome mutagenicity assay, called MPA (Microplate Agar), using TA98 strain. The ten compounds tested were negative for TA98, with and without metabolic activation (S9), except benzo(a)pyrene (Bap), which was positive in the presence of S9, as expected.

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