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Liver enzymes activities, as Gama-GT, Aspartate Transaminase and Alanine Transaminase, were modulated in tumour-bearing rats subjected to early development and weaning periods under leucine and/or omega-3 supplementation. Sarah C. P. de Oliveira*, Natália M. A. da Silva, Maria C. C. Gomes-Marcondes. Abstract Cancer is one of the leading cause of death, being the cachexia state responsible for 25% of deaths. We evaluated the efficiency of nutritional supplementation with leucine and/or omega-3 fatty acid on preventing or minimising the damages caused by Walker-256 carcinoma growth in adult rats from mothers subjected to these dietary schemes during the pregnancy and weaning period. The main proposal was to study the possible epigenetics effects in hepatic tissue, analysing the liver enzymes activities, which confirmed that this supplementation could reduce the metabolic liver impairment.

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Liver enzymes activities, as Gama-GT, Aspartate Transaminase and Alanine Transaminase, were modulated in tumour-bearing rats subjected to early development and weaning periods under leucine and/or omega-3 supplementation.