ASSOCIATION STUDY OF NEPHROTIC SYNDROME IN CHILDREN WITH NEW VARIANTS OF NPHS2 GENE | Zendy

Bárbara de Freitas Carli | Zendy; Mara Sanches Guaragna | Zendy; Maricilda Palandi de Mello | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

ASSOCIATION STUDY OF NEPHROTIC SYNDROME IN CHILDREN WITH NEW VARIANTS OF NPHS2 GENE

Author(s) -

Bárbara de Freitas Carli,

Mara Sanches Guaragna,

Maricilda Palandi de Mello

Publication year - 2016

Publication title -

anais do congresso de iniciação científica da unicamp

Language(s) - English

Resource type - Conference proceedings

ISSN - 2447-5114

DOI - 10.19146/pibic-2016-50605

Subject(s) - nephrotic syndrome , association (psychology) , gene , medicine , genetics , biology , psychology , psychotherapist

This project aimed to screen four variants (SNVs) which were previously identified in the promoter region of the gene NPHS2 in children with nephrotic syndrome, in controls without renal disease. Therefore, we used two different methods after DNA extraction: polymerase chain reaction (PCR) with subsequent sequencing by Sanger method and real time PCR with TaqMan allelic discrimination kit. Only one of the controls presented the c.-268C>G SNV in heterozygosis confirming the rarity of these SNVs .

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research