Why Synergism between Researches and Orthopaedics is still not Enough? Role of IL-1 Beta in Blood Induced Cartilage Damage

More than two decades ago, the concept of tissue engineering predicted the healing of injured tissues and organs by the use of living cells and/or smart functional materials. The approaches taken to recreate tissues and organs have typically involved a combination of cells, materials and bioactive molecules. Combining all the components involved in tissue repair, the hypothesis that “bench neo-created tissue”, upon implantation could lead to host native tissue homeostatic state and by consequence restore from the very first beginning functionalities lost with time due to trauma or disease has gained more clear evidences [1].