Open AccessOptimization of a Clinically Relevant Model of White Matter Stroke in Mice: Histological and Functional Evidences
Author(s) -
Abdullah Shafique Ahmad,
Irawan Satriotomo,
Jawad Fazal,
Stephen E. Nadeau,
Sylvain Doré
Publication year - 2015
Publication title -
journal of neurology and neurosurgery
Language(s) - English
Resource type - Journals
ISSN - 2373-8995
DOI - 10.19104/jnn.2015.14
Subject(s) - white matter , medicine , internal capsule , stroke (engine) , lesion , corpus callosum , gliosis , splenium , pathology , magnetic resonance imaging , radiology , mechanical engineering , engineering
White matter (WM) injury during stroke increases the risk of disability and gloomy prognosis of post-stroke rehabilitation. However, modeling of WM loss in rodents has proven to be challenging.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom