Chimerism in Humans after Bone Marrow Transplantation: A New Challenge for Forensic DNA Experts
Author(s) -
Garima Chaudhary
Publication year - 2016
Publication title -
journal of forensic medicine and legal affairs
Language(s) - English
Resource type - Journals
ISSN - 2472-3800
DOI - 10.19104/jfml.2016.104
Subject(s) - bone marrow transplantation , transplantation , forensic science , medicine , dna , bone marrow , biology , pathology , genetics , surgery
When DNA profiling technique is being performed using any biological specimen from the individual, it promises the correct and unambiguous individualization, but in certain cases the forensic scientist may encounter the problem of mixed or completely mismatched DNA profile of a single individual [1,2]. STR’s (short tandem repeat) may lead to erroneous conclusion when the source of the biological material being analyzed is from a person who is a genetic chimera. In forensic genetics context, such genetic peculiarity may prevent the association of the perpetrator of an offence with the stain left at the crime scene or lead to false Identification of any suspect [2].
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