Studi Histopatologi dan Kadar Timbal pada Ginjal Sapi Bali di Tempat Pembuangan Akhir Suwung Denpasar

The purpose of this research was measure the content of heavy metal like Lead and histopathological changes of bali cattle’s kidneys that is maintained in Suwung Denpasar Landfill. This research use 5 cattle maintained in landfill. The cattle are necropsied and then kidneys organs are taken as samples and then split into two, one to research heavy metal Lead with Atomic Absorption Spectrophotometry (AAS) method. The other is used to make histopathologic preparation with embedded block paraffin technique and Hematoxilin-Eosin coloring. The examination result of 5 kidneys samples of bali cattles overall are found with contamination of heavy metal Lead with variation of 0,5829 ppm, 1,0504 ppm, 1,0505 ppm, 1,1305 ppm until 1,1306 ppm. While the histopathological examination overall show changes of inflammatory cell infiltration, fatty degeneration, and necrosis. This histopathological changes may be caused by toxicity of heavy metal lead that accumulates inside kidneys. Other than that, uncontrolled factors may take effect. Further research about pure heavy metal Lead without other factors that can affect the kidney histopathologic is needed.