The Environmental Factors Influencing the Development of Atopic Diseases Discussed In 2532 Children

Prediction of atopic disorders is an important step and should be carried out by examining both genetic factors and neonatal conditions. It has been known for centuries that heredity plays an important role in the development of atopy. A child with a negative family history still has about a 5-15% risk of developing atopy. However, children with a parental history of atopic disease are at higher risk for the development of atopic symptoms. It has been found that if one parent is affected, the chances of an offspring being affected vary between 20 and 4O%. If both parents are affected the figure increases up to 4060%, and 50-80% if both show the same allergic manifestations. The risk of atopy in children who have an allergic sibling ranges between 25 and 35% [3,10].