High Recovery of Functional Islets Stored at Low and Ultralow Temperatures | Zendy

Bhawna Chandravanshi | Zendy; Anandh Dhanushkodi | Zendy; Ramesh Bhonde | Zendy

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High Recovery of Functional Islets Stored at Low and Ultralow Temperatures

Author(s) -

Bhawna Chandravanshi,

Anandh Dhanushkodi,

Ramesh Bhonde

Publication year - 2014

Publication title -

the review of diabetic studies

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.701

H-Index - 41

eISSN - 1614-0575

pISSN - 1613-6071

DOI - 10.1900/rds.2014.11.267

Subject(s) - islet , propidium iodide , oxidative stress , chemistry , cryoprotectant , pancreatic islets , cold storage , lipid peroxidation , oxidative phosphorylation , insulin , medicine , biochemistry , endocrinology , cryopreservation , apoptosis , biology , microbiology and biotechnology , programmed cell death , embryo , horticulture

Poor recovery of islets upon cryopreservation is the main hurdle in islet banking. Pancreatic islets have a poor antioxidative defense mechanism, and exposure of islets to low temperature leads to oxidative stress.

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