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Paradoxical Negative HDL Cholesterol Response to Atorvastatin and Simvastatin Treatment in Chinese Type 2 Diabetic Patients
Author(s) -
YuHung Chang,
KunCheng Lin,
DaoMing Chang,
Chang-Hsun Hsieh,
Lee Yau-Jiunn
Publication year - 2013
Publication title -
the review of diabetic studies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 41
eISSN - 1614-0575
pISSN - 1613-6071
DOI - 10.1900/rds.2013.10.213
Subject(s) - simvastatin , atorvastatin , medicine , cholesterol , type 2 diabetes , type 2 diabetes mellitus , cholesterol lowering , endocrinology , diabetes mellitus
There is extensive but controversial evidence on the diverse effects of statins on the level of high-density lipoprotein cholesterol (HDL-C). Some of these effects may limit the benefits of statins in terms of cardiovascular risk reduction. To identify the conditions for beneficial effects, this study investigated the response to atorvastatin and simvastatin treatment in type 2 diabetic patients with elevated low-density lipoprotein cholesterol (LDL-C).

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