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Chronic granulomatous disease (CGD) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. This disorder results in recurrent life-threatening bacterial and fungal infections. Aspergillus species are the most common fungal infections in these patients.

Osteomyelitis and lung abscess due to Aspergillus fumigatus in a chronic granulomatous disease patient