Racial Disparities in Creatinine-based Kidney Function Estimates Among HIV-infected Adults | Zendy

Naomi Anker | Zendy; Rebecca Scherzer | Zendy; Carmen A. Peralta | Zendy; Neil R. Powe | Zendy; Tanushree Banjeree | Zendy; Michael G. Shlipak | Zendy

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Racial Disparities in Creatinine-based Kidney Function Estimates Among HIV-infected Adults

Author(s) -

Naomi Anker,

Rebecca Scherzer,

Carmen A. Peralta,

Neil R. Powe,

Tanushree Banjeree,

Michael G. Shlipak

Publication year - 2016

Publication title -

ethnicity and disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.767

H-Index - 67

eISSN - 1945-0826

pISSN - 1049-510X

DOI - 10.18865/ed.26.2.213

Subject(s) - medicine , renal function , kidney disease , cohort , creatinine , veterans affairs , human immunodeficiency virus (hiv) , retrospective cohort study , urology , immunology

The aim of our study was to investigate whether current eGFR equations in clinical use might systematically over-estimate the kidney function, and thus misclassify CKD status, of Black Americans with HIV. Specifically, we evaluated the impact of removing the race coefficient from the MDRD and CKD-EPI equations on comparisons between Black and White HIV-infected veterans related to: 1) the prevalence of reduced eGFR; 2) the distribution of eGFR values; and 3) the relationship between eGFR and all-cause mortality.

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