Open AccessMET exon 14 skipping defines a unique molecular class of non-small cell lung cancer
Author(s) -
Difan Zheng,
Rui Wang,
Ting Ye,
Su Jeong Yu,
Haichuan Hu,
Xuxia Shen,
Yuan Li,
Hongbin Ji,
Yihua Sun,
Haiquan Chen
Publication year - 2016
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.9541
Subject(s) - kras , exon , lung cancer , medicine , exon skipping , oncology , lung , cancer , cancer research , alternative splicing , biology , colorectal cancer , gene , genetics
Recurrent MET exon 14 splicing has been revealed in lung cancers and is a promising therapeutic target. Because we have limited knowledge about the natural history of MET mutant tumors, the current study was aiming to determine the clinical and pathological characteristics in non-small cell lung cancers (NSCLC).
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