Tumor deposits: markers of poor prognosis in patients with locally advanced rectal cancer following neoadjuvant chemoradiotherapy | Zendy

Lu-Ning Zhang | Zendy; Weiwei Xiao | Zendy; Shao-Yan Xi | Zendy; PuYun OuYang | Zendy; Kai-Yun You | Zendy; Zhi-Fan Zeng | Zendy; Pei-Rong Ding | Zendy; Hui-Zhong Zhang | Zendy; Zhi-Zhong Pan | Zendy; RuiHua Xu | Zendy; Yuanhong Gao | Zendy

Open Access

Tumor deposits: markers of poor prognosis in patients with locally advanced rectal cancer following neoadjuvant chemoradiotherapy

Author(s) -

Lu-Ning Zhang,

Weiwei Xiao,

Shao-Yan Xi,

PuYun OuYang,

Kai-Yun You,

Zhi-Fan Zeng,

Pei-Rong Ding,

Hui-Zhong Zhang,

Zhi-Zhong Pan,

RuiHua Xu,

Yuanhong Gao

Publication year - 2015

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.6656

Subject(s) - medicine , colorectal cancer , oncology , cancer , chemoradiotherapy , china , political science , law

Tumor deposits (TDs) were reported to be poor prognoses in colorectal carcinoma, but the significance in locally advanced rectal cancer (LARC) (T3-4/N+) following neoadjuvant chemoradiotherapy (neo-CRT) and surgery is unclear. Since adjuvant chemotherapy showed no benefit for LARC following neo-CRT, it is of great value to investigate whether TDs can identify the subgroup of patients who may benefit from adjuvant chemotherapy.

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