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Recurrent genetic abnormalities that correlate with clinical features could be used to determine patients' prognosis, select treatments and predict responses to therapy. Esophageal squamous cell carcinoma (ESCC) contains genomic alterations of undefined clinical significance. We aimed to identify mutually exclusive mutations that are frequently detected in ESCCs and characterized their associations with clinical variables.

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Mutually exclusive mutations in<i>NOTCH1</i>and<i>PIK3CA</i>associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China

Mutually exclusive mutations inNOTCH1andPIK3CAassociated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China