Mutually exclusive mutations inNOTCH1andPIK3CAassociated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China | Zendy

Bin Song | Zendy; Heyang Cui | Zendy; Yaoping Li | Zendy; Caixia Cheng | Zendy; Bin Yang | Zendy; Fang Wang | Zendy; Pengzhou Kong | Zendy; Hongyi Li | Zendy; Ling Zhang | Zendy; Zhiwu Jia | Zendy; Yanghui Bi | Zendy; Jiaqian Wang | Zendy; Yong Zhou | Zendy; Jing Liu | Zendy; Juan Wang | Zendy; Zhenxiang Zhao | Zendy; Yanyan Zhang | Zendy; Xiao Hu | Zendy; Ruyi Shi | Zendy; Jie Yang | Zendy; Haiyan Liu | Zendy; Ting Yan | Zendy; Yike Li | Zendy; Enwei Xu | Zendy; Yu Qian | Zendy; Yanfeng Xi | Zendy; Shiping Guo | Zendy; Yunqing Chen | Zendy; Jinfen Wang | Zendy; Guodong Li | Zendy; Jianfang Liang | Zendy; Junmei Jia | Zendy; Xing Chen | Zendy; Jiansheng Guo | Zendy; Tong Wang | Zendy; Yanbo Zhang | Zendy; Qingshan Li | Zendy; Chuangui Wang | Zendy; Xiaolong Cheng | Zendy; Qimin Zhan | Zendy; Yongping Cui | Zendy

Open Access

Mutually exclusive mutations inNOTCH1andPIK3CAassociated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China

Author(s) -

Bin Song,

Heyang Cui,

Yaoping Li,

Caixia Cheng,

Bin Yang,

Fang Wang,

Pengzhou Kong,

Hongyi Li,

Ling Zhang,

Zhiwu Jia,

Yanghui Bi,

Jiaqian Wang,

Yong Zhou,

Jing Liu,

Juan Wang,

Zhenxiang Zhao,

Yanyan Zhang,

Xiao Hu,

Ruyi Shi,

Jie Yang,

Haiyan Liu,

Ting Yan,

Yike Li,

Enwei Xu,

Yu Qian,

Yanfeng Xi,

Shiping Guo,

Yunqing Chen,

Jinfen Wang,

Guodong Li,

Jianfang Liang,

Junmei Jia,

Xing Chen,

Jiansheng Guo,

Tong Wang,

Yanbo Zhang,

Qingshan Li,

Chuangui Wang,

Xiaolong Cheng,

Qimin Zhan,

Yongping Cui

Publication year - 2015

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.6120

Subject(s) - medicine , chemotherapy , oncology , univariate analysis , esophageal squamous cell carcinoma , malignancy , proportional hazards model , multivariate analysis , mutation , stage (stratigraphy) , survival analysis , carcinoma , gene , biology , genetics , paleontology

Recurrent genetic abnormalities that correlate with clinical features could be used to determine patients' prognosis, select treatments and predict responses to therapy. Esophageal squamous cell carcinoma (ESCC) contains genomic alterations of undefined clinical significance. We aimed to identify mutually exclusive mutations that are frequently detected in ESCCs and characterized their associations with clinical variables.

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