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Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas
Author(s) -
Tareq A. Juratli,
Christian Thiede,
Mara V.A. Koerner,
Shilpa S. Tummala,
Dirk Daubner,
Ganesh M. Shankar,
Erik A. Williams,
María Martínez-Lage,
Silke Soucek,
Katja Robel,
Tristan Penson,
Mechthild Krause,
Steffen Appold,
Matthias Meinhardt,
Thomas Pinzer,
Julie J. Miller,
Dietmar Krex,
Heather A. Ely,
Ian M. Silverman,
Jason Christiansen,
Gabriele Schackert,
Hiroaki Wakimoto,
Matthias Kirsch,
Priscilla K. Brastianos,
Daniel P. Cahill
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.22650
Subject(s) - medicine , german , philosophy , linguistics
Recent studies have reported mutations in the telomerase reverse transcriptase promoter ( TERT p) in meningiomas. We sought to determine the frequency, clonality and clinical significance of telomere gene alterations in a cohort of patients with progressive/higher-grade meningiomas.

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