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Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population
Author(s) -
Eugene Lin,
PoHsiu Kuo,
YuLi Liu,
Albert C. Yang,
ShihJen Tsai
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.20967
Subject(s) - genome wide association study , single nucleotide polymorphism , medicine , metabolic syndrome , waist , population , epidemiology , genetic association , gerontology , genetics , obesity , biology , environmental health , gene , genotype
Although the association of single nucleotide polymorphisms (SNPs) with metabolic syndrome (MetS) has been reported in various populations in several genome-wide association studies (GWAS), the data is not conclusive. In this GWAS study, we assessed whether SNPs are associated with MetS and its individual components independently and/or through complex interactions in a Taiwanese population.

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