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Effects of growth hormone on cardiac remodeling and soleus muscle in rats with aortic stenosis-induced heart failure
Author(s) -
A. R. R. Lima,
Luana Urbano Pagan,
Ricardo Luiz Damatto,
M. D. M. Cezar,
Camila Bonomo,
Mariana Janini Gomes,
Paula Felippe Martinez,
Daniele M. Guizoni,
Dijon Henrique Salomé de Campos,
F C Damatto,
Katashi Okoshi,
Marina Politi Okoshi
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.20583
Subject(s) - medicine , endocrinology , heart failure , stenosis , soleus muscle , cardiology , skeletal muscle
Skeletal muscle wasting is often observed in heart failure (HF). The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis is impaired in HF. In this study, we evaluated the effects of GH on soleus muscle and cardiac remodeling in rats with aortic stenosis (AS)-induced HF.

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