Antibiotic prophylaxis for infections in patients with acute stroke: a systematic review and meta-analysis of randomized controlled trials | Zendy

Yanguo Xi | Zendy; Xu Tian | Zendy; Wei-Qing Chen | Zendy; Sai Zhang | Zendy; Shan Zhang | Zendy; Ren Weidan | Zendy; Qi-jun Pang | Zendy; Guotao Yang | Zendy; Yang Zhi-ming | Zendy

Open Access

Antibiotic prophylaxis for infections in patients with acute stroke: a systematic review and meta-analysis of randomized controlled trials

Author(s) -

Yanguo Xi,

Xu Tian,

Wei-Qing Chen,

Sai Zhang,

Shan Zhang,

Ren Weidan,

Qi-jun Pang,

Guotao Yang,

Yang Zhi-ming

Publication year - 2017

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.19039

Subject(s) - medicine , meta analysis , stroke (engine) , relative risk , randomized controlled trial , cochrane library , antibiotic prophylaxis , adverse effect , antibiotics , confidence interval , incidence (geometry) , intensive care medicine , mechanical engineering , physics , microbiology and biotechnology , optics , engineering , biology

Infections are frequent after stroke and lead to increased mortality and neurological disability. Antibiotic prophylaxis has potential of decreasing the risk of infections and mortality and improving poor functional outcome. Several studies evaluated antibiotic prophylaxis for infections in acute stroke patients have generated conflicting results. The systematic review of randomized clinical trials (RCTs) aimed at comprehensively assessing the evidence of antibiotic prophylaxis for the treatment of acute stroke patients.

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