Impact of phosphoinositide-3-kinase and vitamin D3 nuclear receptor single-nucleotide polymorphisms on the outcome of malignant melanoma patients | Zendy

Francesca Morgese | Zendy; Davide Soldato | Zendy; Silvia Pagliaretta | Zendy; Riccardo Giampieri | Zendy; Donatella Brancorsini | Zendy; Mariangela Torniai | Zendy; Silvia Rinaldi | Zendy; Agnese Savini | Zendy; Azzurra Onofri | Zendy; Marina Scarpelli | Zendy; Rossana Berardi | Zendy

Open Access

Impact of phosphoinositide-3-kinase and vitamin D3 nuclear receptor single-nucleotide polymorphisms on the outcome of malignant melanoma patients

Author(s) -

Francesca Morgese,

Davide Soldato,

Silvia Pagliaretta,

Riccardo Giampieri,

Donatella Brancorsini,

Mariangela Torniai,

Silvia Rinaldi,

Agnese Savini,

Azzurra Onofri,

Marina Scarpelli,

Rossana Berardi

Publication year - 2017

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.18304

Subject(s) - calcitriol receptor , single nucleotide polymorphism , genotype , medicine , oncology , progression free survival , cancer research , biology , genetics , vitamin d and neurology , gene , overall survival

Several studies associating single nucleotide polymorphisms (SNPs) frequencies with tumors outcome have been conducted, nevertheless malignant melanoma literature data are inconclusive.Therefore we evaluate the impact of different genotypes for phosphoinositide-3-kinase (PI3K) and vitamin D3 nuclear receptor (VDR) SNPs on melanoma patients' outcome.

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