Open AccessAssociation of STAT4 and PTPN22 polymorphisms and their interactions with type-1 autoimmune hepatitis susceptibility in Chinese Han children
Author(s) -
Xiaofeng Li,
Huiqin Chen,
Yun Cai,
Ping Zhang,
ZhuangGui Chen
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.17458
Subject(s) - ptpn22 , haplotype , genotype , single nucleotide polymorphism , allele , medicine , gastroenterology , autoimmune hepatitis , immunology , biology , oncology , genetics , hepatitis , gene
To investigate the impact of signal transducer and activator of transcription 4 (STAT4) and the protein tyrosine phosphatase N22 (PTPN22) gene single nucleotide polymorphisms (SNPs), gene-gene interactions and haplotype on type-1 Autoimmune Hepatitis (AIH) risk.
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